Technology is not a replacement for democracy | Science
A government run by machines is not inevitable—we have been here and rejected it before
Bonding carbons iteratively | Science
A modular synthesis method could broaden the accessibility of chemistry
The lab that learns | Science
Integrating high-throughput experiments, robotics, and artificial intelligence can accelerate scientific discoveries
RAD51 stabilizes neutrophil extracellular traps to compartmentalize inflammation | Science
Neutrophil extracellular traps (NETs) feature a branched chromatin architecture whose origin and function remain unknown. We found that NET branching is mediated by RAD51, a protein generating DNA junctions during DNA recombination repair. ...
Modality-specific neurovascular coupling via layer-segregated arteriole networks | Science
The brain’s vascular system dynamically regulates energy supply through neurovascular coupling. In this study, we show that in mice, neurovascular coupling is modality-dependent: Distinct sensory inputs recruit specific arteriole types, producing ...
Tracing the origins of de novo coronary collateral formation in cardiac repair | Science
Coronary collateral arteries have been proposed to form de novo through artery reassembly, a process in which arterial endothelial cells (ECs) migrate away from preexisting arteries and reassemble into new arteries. Using genetic tools that trace ...
TGW1a locus simultaneously shortens growth duration and boosts grain yield in rice | Science
Reconciling the trade-off between short growth duration and high grain yield is essential for enhancing annual rice yields. We found that qTGW1a, encoding a flowering locus T-like protein, controls heading and nitrogen use efficiency (NUE) underpinning ...
Genomes of Poaceae relatives reveal key metabolic innovations preceding the evolution of grasses | Science
The grass family (Poaceae) has immense economic and ecological importance and exhibits distinctive metabolic traits, including dual starch and lignin biosynthetic pathways. We sequenced the genomes of Pharus, Joinvillea, Ecdeiocolea, and Typha species to ...
Experiences and economic decision-making | Science
It is often said that we are nothing but the sum of our experiences. The accumulation of past experiences matters for economic behavior in any given moment: They can shape the objectives and goals we set, the perceived constraints around choices to be made, and they help form our attitudes and views of the world around us. A fast-growing literature in economics studies such experience effects, drawing together work in sociology, social psychology, and neuroscience, to understand how past experiences sink into memory, are recalled when making decisions, and compete with other relevant sources of information we might have, to shape consequential behaviors throughout life.
In Other Journals | Science
Editors’ selections from the current scientific literature