Una investigación de Science arroja dudas sobre genes prometedores para prevenir la enfermedad de Alzheimer
Mutaciones encontradas en familias colombianas dieron esperanza para el desarrollo de tratamientos. Datos alterados e imágenes sospechosas ponen en cuestión los beneficios
A cross-organ single-cell analysis of hypertension | Science
Hypertension is a leading cause of disease burden and mortality. Here, we present a single-cell analysis of hypertension and end-organ damage across six organs and tissues in angiotensin II–treated mice, Dahl salt–sensitive rats, and spontaneously ...
The eukaryote chromosome, a two-state system with interconversion by a volume phase transition | Science
The formation of metaphase chromosomes requires the activity of condensins, DNA translocases that reduce chromosomal length through the process of loop extrusion. Reduction of length, however, does not account for the increase in density of chromatin in ...
Should humanoid robots in every household really be a top priority? | Science
It is likely that you have seen videos of humanoid robots diligently performing a variety of household chores: loading the dishwasher, vacuuming the floor, or putting groceries away. These are all tasks we humans carry out regularly, usually with limited enthusiasm, that often prevent us from doing considerably more interesting things. I shall refrain from elaborating on what those things might be, save to suggest that reading this piece would not be an entirely unreasonable choice, and instead turn to a question that has occupied me for rather more months than I care to admit—is loading the dishwasher really among the most pressing problems we need robots to solve today?
Xylose phosphatase activity of dystroglycan self-regulates its receptor function | Science
Dystroglycan (DG) is an extracellular matrix receptor crucial for tissue development and pathogen entry. DG harbors a long, complex glycan called matriglycan. Loss of matriglycan or reduction in its length disrupts DG function, causing ...
A joint geophysical-geochemical deep-mantle zoning map beneath East Africa and the Indian Ocean | Science
Geochemical signatures of hotspot lavas suggest that their mantle sources are compositionally distinct, but their source locations remain elusive. Mapping hotspots to their deep origins is complicated by the presence of interconnected, low–seismic ...
In Other Journals | Science
Editors’ selections from the current scientific literature
In Science Journals | Science
Highlights from the Science family of journals
False reporting undermines the integrity of supply chain sustainability initiatives | Science
A field experiment among Côte d’Ivoire cocoa farms suggests an approach to improve auditor reporting
Shark governance requires species identity | Science
More than a decade after shark mislabeling was first highlighted in Brazil (1), generic commercial names such as caçao (2–4), galeos (5), rock salmon and huss (6), flake (7), palombo (8), tollo, and cazón (9) continue to obscure shark species identity worldwide. DNA-based surveys repeatedly reveal that products sold under these names comprise multiple shark species, including threatened and internationally regulated taxa (2–12). Although these commercial names differ among countries, they produce the same outcome: species identity is progressively lost as shark products move from capture to consumption, precisely where fisheries management, wildlife trade regulation, sustainability claims, and informed consumer choice depend on it.